FB23-2, FTO inhibitor, 25mg, CAS# 2243736-45-8
$240.00
2-[2,6-Dichloro-4-(3,5-dimethyl-1,2-oxazol-4-yl)anilino]-N-hydroxybenzamide Purity: 98% by HPLC NMR (Conforms) Store -20°C Ship RT (1 per EA )
Manufacturer: Focus Biomolecules
SKU
10-4852-25mg-EA
FB23-2, FTO inhibitor, 25mg, CAS# 2243736-45-8 is available to buy in increments of 1
Product Details
Download Details and SpecificationsFB23-2 is an inhibitor (IC50 = 2.6 µM) of the mRNA m6A demethylase fat-mass- and obesity-associated protein (FTO).1 Displays significant anti-proliferative activity in NB4 (IC50 = 0.8 µM) and MONOMAC6 (IC50 = 1.5 µM) cells. Selective against the RNA demethylase ALKB5. FB23-2 induced myeloid differentiation and apoptosis in acute myeloid leukemia cells. FB23-2 suppressed the proliferation and migration of hepatocellular carcinoma cells via suppressing the expression of the kinase ERBB3 and human tubulin beta class Iva (TUBB4A).2
CAS Number: 2243736-45-8
Manufacturer Part Number/SKU: 10-4852-25mg-EA
Tags: Focus Biomolecules