Manufacturer: Focus Biomolecules
EN450 is a molecular glue that covalently interacts with a cysteine residue on the E2 ubiquitin ligase UBE2D. It displayed anti-proliferative effects in HAP1 leukemia cells. EN450s antiproliferative effects were elicited via proteasome-dependent degradation of nuclear factor kappa B subunit 1(NFkB1).1
CAS Number: 793719-01-4
Manufacturer Part Number/SKU: 10-3936-5mg-EA
Tags: Focus Biomolecules