Manufacturer: Focus Biomolecules
Echinomycin is a potent and selective hypoxia inducible factor 1α (HIF-1α) inhibitor. It binds to DNA via bifunctional intercalation, blocking the interaction of HIF-1α.1 Protects mice against relapsed acute myeloid leukemia with no effect on hematopoietic stem cells.2 Selectively eliminates cancer stem cells in mouse lymphoma and human AML xenogeneic models.3 A very useful tool for probing genes regulated by HIF1α.4
CAS Number: 512-64-1
Manufacturer Part Number/SKU: 10-2424-5mg-EA
Tags: Focus Biomolecules