Dovitinib, Kinase inhibitor, 5mg, CAS# 405169-16-6
$75.00
4-Amino-5-fluoro-3-[5-(4-methylpiperazin-1-yl)-1H-benzimidazol-2-yl]quinolin-2(1H)-one Purity: 99% by TLC Purity: 99% by HPLC Store -20°C Ship RT (1 per EA )
Manufacturer: Focus Biomolecules
SKU
10-2129-5mg-EA
Dovitinib, Kinase inhibitor, 5mg, CAS# 405169-16-6 is available to buy in increments of 1
Product Details
Download Details and SpecificationsPotent kinase inhibitor. Inhibits FLT3 (IC50 = 1 nM), c-KIT (IC50 = 2 nM), FGFR (IC50 = 8 nM), VEGFR1/2/3 (IC50 = 10 nM), PDGFRβ (IC50 = 27 nM), and CSF-1R (IC50 = 36 nM).1 Active in cell culture and in whole animals. Selectively blocks the growth B9 cells transformed by wild type, or activated mutant FGFR3. Induces apoptosis, or sensitizes cells to induction of apoptosis by other means in a variety of cancer cell lines.
CAS Number: 405169-16-6
Manufacturer Part Number/SKU: 10-2129-5mg-EA
Tags: Focus Biomolecules