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Dorsomorphin, AMPK inhibitor, 25mg, CAS# 866405-64-3

$190.00
6-[4-[2-(1-Piperidinyl)ethoxy]phenyl]-3-(4-pyridinyl)-pyrazolo[1,5-a]pyrimidine Purity: 98% by TLC Purity: NMR (Conforms) Store -20°C Ship RT (1 per EA )

Manufacturer: Focus Biomolecules

SKU
10-1029-25mg-EA
Dorsomorphin, AMPK inhibitor, 25mg, CAS# 866405-64-3 is available to buy in increments of 1

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Potent, selective and ATP-competitive inhibitor of AMP-activated protein kinase (AMPK) (Ki = 109 nM).1 It displays no significant inhibition of ZAPK, SYK, PKCT, PKA and JAK3. It inhibits bone morphogenetic protein (BMP) type I receptors (ALK2, ALK3 and ALK6).2 Dorsomorphin has been shown to promote cardiomyogenesis in mouse embryonic stem cells (ESCs) in vitro.3 Induces autophagy in cancer cell lines via a mechanism independent of AMPK inhibition.4

CAS Number: 866405-64-3

Manufacturer Part Number/SKU: 10-1029-25mg-EA

Tags: Focus Biomolecules