DMXAA, Mouse STING activator, 5mg, CAS# 117570-53-3
$60.00
5,6-Dimethylxanthenone-4-acetic acid Purity: 98% by TLC NMR (Conforms) Store RT Ship RT (1 per EA )
Manufacturer: Focus Biomolecules
SKU
10-2676-5mg-EA
DMXAA, Mouse STING activator, 5mg, CAS# 117570-53-3 is available to buy in increments of 1
Product Details
Download Details and SpecificationsSTING (Stimulator of Interferon Genes) agonist selective for mouse STING.1,2 Intratumoral administration of DMXAA resulted in tumor regression and complete rejection in mouse xenografts.3 Tumor regression induced by DMXAA results from a cascade of cellular events which include disruption of tumor vasculature followed by the release of chemokines which trigger the recruitment of immune cells.4 DMXAA induced expression of IFN-b resulting in a striking expansion of leukemia-specific T cells extending survival in two acute myeloid leukemia models.5
CAS Number: 117570-53-3
Manufacturer Part Number/SKU: 10-2676-5mg-EA
Tags: Focus Biomolecules