Dienamide A2, Novel cannabinoid CB2 agonist; antiinflammatory, 5mg, CAS# 24738-51-0
$60.00
(2E,4E)-N-Isobutyldodeca-2,4-dienamide Purity: 98% by TLC NMR conforms Store -20°C Ship Blue Ice (1 per EA )
Manufacturer: Focus Biomolecules
SKU
10-1621-5mg-EA
Dienamide A2, Novel cannabinoid CB2 agonist; antiinflammatory, 5mg, CAS# 24738-51-0 is available to buy in increments of 1
Product Details
Download Details and SpecificationsAnalog of the natural amides occurring in Echinacea which represent a new class of cannabinomimetic compounds. This class of compounds modulates TNFα mRNA expression in human monocytes/macrophages via the CB2 receptor.1 Dienamide A2 binds to cannabinoid receptors with greater affinity than endogenous cannabinoids (Ki= ~60 and >1500 nM for CB2 and CB1 respectively)2. It elevates intracellular Ca2+ levels in CB2-positive but not in CB2-negative cells and this effect was blocked by SR144528.2 It significantly inhibits LPS-induced TNFα and IL-1β expression in a CB2-independent manner.2
CAS Number: 24738-51-0
Manufacturer Part Number/SKU: 10-1621-5mg-EA
Tags: Focus Biomolecules