Cytarabine, DNA synthesis and transcription disruptor, 2g, CAS# 147-94-4
$90.00
4-Amino-1-ß-D-arabinofuranosyl-2(1H)-pyrimidinone Purity: 98% by HPLC NMR (Conforms) Store -20°C Ship RT (1 per EA )
Manufacturer: Focus Biomolecules
SKU
10-1268-2g-EA
Cytarabine, DNA synthesis and transcription disruptor, 2g, CAS# 147-94-4 is available to buy in increments of 1
Product Details
Download Details and SpecificationsA nucleoside analog that interferes with DNA synthesis and transcription, particularly in tumor cells.1,2 It Cellular enzymes convert it to its nucleotide form, Ara-CTP, which disrupts DNA and RNA synthesis when polymerases attempt to incorporate it.3,4 For the same reasons, it is also employed as an antiviral.5 It inhibits proliferation of a variety of leukemic cell lines (IC50s 16-72 nM), but is used primarily against acute myeloid leukemia (AML).6,7
CAS Number: 147-94-4
Manufacturer Part Number/SKU: 10-1268-2g-EA
Tags: Focus Biomolecules