CU-CPT8m, TLR8 antagonist, 5mg, CAS# 125079-83-6
$70.00
7-(3-Methylphenyl)-pyrazolo[1,5-a]pyrimidine-3-carboxamide Purity: >98% by HPLC Purity: NMR (Conforms) Store -20°C Ship RT (1 per EA )
Manufacturer: Focus Biomolecules
SKU
10-3374-5mg-EA
CU-CPT8m, TLR8 antagonist, 5mg, CAS# 125079-83-6 is available to buy in increments of 1
Product Details
Download Details and SpecificationsCU-CPT8m is a potent and selective antagonist of toll-like receptor 8 (TLR8) acting via stabilization of the TLR8 homodimer.1 It inhibits TNFα and IL-8 expression induced by the TLR8 agonist resiquimod at 1 mM and suppresses TLR8-mediated proinflammatory signaling in various cell lines, human primary cells and patient specimens. It reverses phenotypes involved in TLR8-activating fibroblasts.2 CU-CPT8m promotes erythroid cell proliferation and differentiation.3
CAS Number: 125079-83-6
Manufacturer Part Number/SKU: 10-3374-5mg-EA
Tags: Focus Biomolecules