Crizotinib, c-Met and ALK inhibitor, 5mg, CAS# 877399-52-5
$80.00
3-[(1R)-1-(2,6-Dichloro-3-fluorophenyl)ethoxy]-5-[1-(4-piperidinyl)-1H-pyrazol-4-yl]-2-pyridinamine Purity: 98% by HPLC Purity: NMR (Conforms) Store -20°C Ship RT (1 per EA )
Manufacturer: Focus Biomolecules
SKU
10-2626-5mg-EA
Crizotinib, c-Met and ALK inhibitor, 5mg, CAS# 877399-52-5 is available to buy in increments of 1
Product Details
Download Details and SpecificationsA potent and selective inhibitor of c-MET and ALK, IC50s=8 and 20 nM respectively.1 Inhibition of cell proliferation was associated with G1-S phase cell cycle arrest and induction of apoptosis in ALK-positive ALCL cells (IC50=30 nM) but not in ALK-negative lymphoma cells.1 Exhibits cytoreductive antitumor efficacy via antiproliferative and antiangiogenic mechanisms.2 Clinically useful anticancer agent.3
CAS Number: 877399-52-5
Manufacturer Part Number/SKU: 10-2626-5mg-EA
Tags: Focus Biomolecules