CLP-3094, GPR142 antagonist, 5mg, CAS# 312749-73-8
$65.00
2-{[2-(4-Chlorophenoxy)ethyl]thio}-1H-benzimidazole Purity: 98% by TLC NMR (Conforms) Store -20°C Ship RT (1 per EA )
Manufacturer: Focus Biomolecules
SKU
10-3382-5mg-EA
CLP-3094, GPR142 antagonist, 5mg, CAS# 312749-73-8 is available to buy in increments of 1
Product Details
Download Details and SpecificationsGPR142 is highly expressed in the pancreas and immune system and shares 33% homology with GPR1391. Endogenous agonists identified to date include aromatic amino acids such as tryptophan and phenylalanine2. CLP-3094 was identified as a potent and selective GPR142 antagonist with an IC50=2.3 mM against 1 mM L-tryptophan. It inhibited insulin secretion from islets induced by L-tryptophan and other agonists and displayed anti-inflammatory activity in a mouse arthritis model.3
CAS Number: 312749-73-8
Manufacturer Part Number/SKU: 10-3382-5mg-EA
Tags: Focus Biomolecules