Chroman_1, ROCK II inhibitor / Stem cell cytoprotectant, 5mg, CAS# 1273579-40-0
$185.00
(3S)-N-[2,[2-(Dimethylamino)ethoxy)-4-(1H-pyrazol-4-yl)phenyl]-6-methoxy-3,4-dihydro-2H-chromen-3-carboxamide Purity: 99% by HPLC NMR (conforms) Store -20°C Ship RT (1 per EA )
Manufacturer: Focus Biomolecules
SKU
10-4912-5mg-EA
Chroman_1, ROCK II inhibitor / Stem cell cytoprotectant, 5mg, CAS# 1273579-40-0 is available to buy in increments of 1
Product Details
Download Details and SpecificationsExtremely potent inhibitor of Rho kinase II (ROCK-II)1,2 - it displayed greater selectivity and potency compared to Y-27632 (IC50's: ROCK I = 52 pM/ROCK II = 1 pM; Y-27632 IC50's: ROCK I = 71 nM/ROCK II = 46 nM)3. Chroman 1, used in conjunction with trans-ISRIB (Cat# 10-1539), Emricasan (Cat# 10-4280), and polyamines (CEPT cocktail), promotes cytoprotective cell survival in human pluripotent stem cells (hPSCs) and was found to superior to Y-27632.3 Chroman 1 is an important new tool in the generation and maintenance of stem cells.
CAS Number: 1273579-40-0
Manufacturer Part Number/SKU: 10-4912-5mg-EA
Tags: Focus Biomolecules