CGP-37157, MPTP inhibitor, 10mg, CAS# 75450-34-9
$70.00
7-Chloro-5-(2-chlorophenyl)-1,5-dihydro-4,1-benzothiazepin-2(3H)-one Purity: 99% by TLC Store RT Ship RT (1 per EA )
Manufacturer: Focus Biomolecules
SKU
10-4250-10mg-EA
CGP-37157, MPTP inhibitor, 10mg, CAS# 75450-34-9 is available to buy in increments of 1
Product Details
Download Details and SpecificationsInhibits the mitochondrial Na+-Ca2+ exchanger (NCX) in isolated heart mitochondria, IC50=0.36 μM.1 Does not inhibit the plasmalemmal NCX.2 Also inhibits voltage-gated Ca2+ channels in intact cells and therefore its use in cellular studies must employ adequate controls.3 Prevents sudden death in a Guinea pig model of heart failure.4 Displays pronounced cytoprotective effects in chromaffin cells5 and in neuronal injury models.6 Blood-brain barrier permeant.
CAS Number: 75450-34-9
Manufacturer Part Number/SKU: 10-4250-10mg-EA
Tags: Focus Biomolecules