CDDO-Me, Nrf2 activator, 25mg, CAS# 218600-53-4

CDDO-Me, Nrf2 activator, 25mg, CAS# 218600-53-4

SM-164, Smac mimetic, 1mg, CAS# 957135-43-2

SM-164, Smac mimetic, 1mg, CAS# 957135-43-2

CDDO-Me, Nrf2 activator, 5mg, CAS# 218600-53-4

$60.00
2-Cyano-3,12-dioxooleana-1,9(11)-dien-28-oic acid methyl ester Purity: >98% by HPLC NMR (Conforms) Store -20°C Ship RT (1 per EA )

Manufacturer: Focus Biomolecules

SKU
10-5449-5mg-EA
CDDO-Me, Nrf2 activator, 5mg, CAS# 218600-53-4 is available to buy in increments of 1

Product Details

Potent activator of Nrf2 target transcription via interaction with thiol groups of Keap1, an Nrf2 partner, in phase 2 response against oxidative stress.1 Inhibits the NF-κB pathway via inhibition of IKKα activation in vitro2 and reduces expression of proinflammatory cytokines in vivo3. Alters tumor microenvironment causing breast tumor associated macrophages to switch from tumor-promoting to tumor-inhibiting characteristics in vitro.4 Reduces cancer stem cell marker expression in Ec109 and KYSE70 cells.5

CAS Number: 218600-53-4

Manufacturer Part Number/SKU: 10-5449-5mg-EA

Tags: Focus Biomolecules