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CB-103, Notch signaling pathway inhibitor, 20mg, CAS# 218457-67-1

$40.00
5-Amino-2-(4-tert-butylphenoxy)pyridine Purity: 98% by HPLC Purity: NMR (Conforms) Store RT Ship RT (1 per EA )

Manufacturer: Focus Biomolecules

SKU
10-4742-20mg-EA
CB-103, Notch signaling pathway inhibitor, 20mg, CAS# 218457-67-1 is available to buy in increments of 1

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Orally active inhibitor of the Notch signaling activation complex (IC50's from 0.9 to 3.9 µM in various cell-based assays), the most downstream level of the Notch signaling pathway. It inhibited the growth of Notch-addicted human T cell acute lymphoblastic leukemia cells as well as other cell lines. CB-103 also inhibited the growth of human breast cancer and leukemia xenografts without the intestinal toxicity associated with γ-secretase Notch inhibitors.

CAS Number: 218457-67-1

Manufacturer Part Number/SKU: 10-4742-20mg-EA

Tags: Focus Biomolecules