Canagliflozin, SGLT2 inhibitor, 50mg, CAS# 842133-18-0
$160.00
(1S)-1,5-anhydro-1-C-[3-[[5-(4-fluorophenyl)-2-thienyl]methyl]-4-methylphenyl]-D-glucitol Purity: 98% by TLC NMR (Conforms) Store -20°C Ship RT (1 per EA )
Manufacturer: Focus Biomolecules
SKU
10-3576-50mg-EA
Canagliflozin, SGLT2 inhibitor, 50mg, CAS# 842133-18-0 is available to buy in increments of 1
Product Details
Download Details and SpecificationsPotent inhibitor of the sodium-dependent glucose cotransporter 2 (SGLT2), IC50 = 2.2 nM selective over SGLT1, IC50=910 nM.1 Dose dependently increases glucose excretion in healthy subjects.2 Displays beneficial effects in nonalcoholic fatty liver disease (NAFLD).3 Extends lifespan in male but not female mice.4 Inhibits cancer cell proliferation via inhibition of mitochondrial complex-1 supported respiration.5 Suppresses the growth of pancreatic cancer cells.6
CAS Number: 842133-18-0
Manufacturer Part Number/SKU: 10-3576-50mg-EA
Tags: Focus Biomolecules