C-DIM 8, Nur77 antagonist, 5mg, CAS# 151358-47-3
$40.00
1,1-Bis(3’-indolyl)-1-(p-hydroxyphenyl)methane Purity: 98% by TLC Purity: NMR (Conforms) Store -20°C Ship RT (1 per EA )
Manufacturer: Focus Biomolecules
SKU
10-5157-5mg-EA
C-DIM 8, Nur77 antagonist, 5mg, CAS# 151358-47-3 is available to buy in increments of 1
Product Details
Download Details and SpecificationsC-DIM 8 is an antagonist of the orphan nuclear receptor Nur77 (NR4A1, TR3).1 Induces reactive oxygen species and ER stress in pancreatic cancer cells.2 C-DIM 8 mimics the effect of Nur77 knockdown in non-small-cell lung cancer A549 and H460 cells, inhibiting cell growth and inducing apoptosis which was accompanied by decreased expression of survivin and inhibition of mTORC1 signaling.3 Inhibits the expression of β1- and β3-integrin and blocks integrin-dependent breast cancer cell migration.4 Decreases expression of the histone methyltransferase G9A (EHMT2) in a variety of cancer cell lines.5
CAS Number: 151358-47-3
Manufacturer Part Number/SKU: 10-5157-5mg-EA
Tags: Focus Biomolecules