Buparlisib, PI3-kinase inhibitor, 25mg, CAS# 944396-07-0
$230.00
5-(2,6-Dimorpholin-4-ylpyrimidin-4-yl)-4-(trifluoromethyl)pyridine-2-amine Purity: 99% by HPLC Purity: NMR (Conforms) Store -20°C Ship RT (1 per EA )
Manufacturer: Focus Biomolecules
SKU
10-4325-25mg-EA
Buparlisib, PI3-kinase inhibitor, 25mg, CAS# 944396-07-0 is available to buy in increments of 1
Product Details
Download Details and SpecificationsPotent pan-Class I PI3-kinase inhibitor (IC50's: p110α = 52 nM, p110ß = 166 nM, p110δ = 116 nM. P110g = 262 nM).1,2 It inhibited microtubule dynamics at in vitro concentrations >1µM and doses above 50mg/kg in mice.3 Buparlisib lead to a precipitous drop in DNA synthesis in a mouse model of BRCA1-linked triple-negative breast cancer with less affect in normal tissue.4
CAS Number: 944396-07-0
Manufacturer Part Number/SKU: 10-4325-25mg-EA
Tags: Focus Biomolecules