BPTES, Glutaminase GLS1 inhibitor, 5mg, CAS# 314045-39-1
$55.00
N,N’-[Thiobis(2,1-ethanediyl-1,3,4-thiadiazole-5,2-diyl)]bisbenzeneacetamide Purity: 98% by TLC Purity: NMR (Conforms) Store -20°C Ship RT (1 per EA )
Manufacturer: Focus Biomolecules
SKU
10-5414-5mg-EA
BPTES, Glutaminase GLS1 inhibitor, 5mg, CAS# 314045-39-1 is available to buy in increments of 1
Product Details
Download Details and SpecificationsPotent and selective allosteric1 inhibitor of kidney-type glutaminase (GLS1), IC50 = 3.3 µM2. Selective for GLS1 over GLS2, g-glutamyl transpeptidase and glutamate dehydrogenase. Shuts down an alternative energy-generating glutaminolysis pathway in P493 cells under both glucose deprivation or hypoxia.3 Reduces the growth of P493 cell xenografts by 50% over a 10 day treatment.4 BPTES inhibition of glutamine utilization in cancer cells increases PD-L1 expression.5 Clears senescent cells and improves various age-related disorders in a geriatric mouse model.6
CAS Number: 314045-39-1
Manufacturer Part Number/SKU: 10-5414-5mg-EA
Tags: Focus Biomolecules