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BO-264, TACCS inhibitor, 25mg, CAS# 2408648-20-2

$240.00
3-(4-Methoxyphenyl)-N-(2-morpholin-4-ylpyrimidin-4-yl)-1,2-oxazol-5-amine Purity: 99% by HPLC NMR (Conforms) Store -20°C Ship RT (1 per EA )

Manufacturer: Focus Biomolecules

SKU
10-4685-25mg-EA
BO-264, TACCS inhibitor, 25mg, CAS# 2408648-20-2 is available to buy in increments of 1

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BO-264 is a potent (IC50 = 188 nM) inhibitor of transforming acidic coiled-coil 3 (TACC3), an important protein involved in microtubule stability and centrosome integrity.1 TACC3 is frequently upregulated in a broad range of cancers. BO-264 displayed significant anticancer activity in greater than 90% of cell lines in the NCI-60 human cancer cell line panel. Active in vivo in mice injected with JIMT-1 and EMT6 breast cancer cells as well as mouse colon cancer xenografts HCT-116 and CT-26.

CAS Number: 2408648-20-2

Manufacturer Part Number/SKU: 10-4685-25mg-EA

Tags: Focus Biomolecules