Manufacturer: Focus Biomolecules
Potent and selective ATP citrate lyase (ACL) inhibitor, IC50=0.13 mM. Inhibits lipid biosynthesis, IC50=8 mM in HepG2 cells.1,2 Reduces weight gain, lowers plasma cholesterol, triglycerides and glucose in high-fat-fed mice.2 A novel tool compound for exploring the potential of ACL inhibition as a target for metabolic disorders such as obesity and dyslipidemia.2 Impairs proliferation or induces death in androgen-depleted castration resistant prostate cancer cells.3 Reduces cell cycle progression in iBN cells.4
CAS Number: 943962-47-8
Manufacturer Part Number/SKU: 10-1414-25mg-EA
Tags: Focus Biomolecules