BIX-01294, Histone Methyl transferase inhibitor+D257, 25mg, CAS# 935693-62-2
$240.00
2-(Hexahydro-4-methyl-1H-1,4-diazepin-1-yl)-6,7-dimethoxy-N-[1-(phenylmethyl)-4-piperidinyl]-4-quinazolinamine trihydrochloride Purity: >98% by HPLC Store RT Ship RT (1 per EA )
Manufacturer: Focus Biomolecules
SKU
10-1335-25mg-EA
BIX-01294, Histone Methyl transferase inhibitor+D257, 25mg, CAS# 935693-62-2 is available to buy in increments of 1
Product Details
Download Details and SpecificationsBIX-01294 is a selective inhibitor of G9a histone methyltransferase (G9aHMTase; IC50 = 1.7 µM) as well as GLP HMTase (IC50 = 38 µM) leading to a decrease in H3K9me2(histone H3 lysine 9 methylation) in vitro.1 BIX-01294 facilitates the reactivation of pluripotency genes and induces passive demethylation, thus promoting reprogramming. BIX-01294, in combination with BAY K8644 (a calcium channel agonist), was found to improve reprogramming efficiencies of Oct4-Klf4-(OK)-infected neural progenitor cells.3
CAS Number: 935693-62-2
Manufacturer Part Number/SKU: 10-1335-25mg-EA
Tags: Focus Biomolecules