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Biotin-isoxazole, Precipitates RNA Binding Proteins, 5mg, CAS# 1377605-22-5

$360.00
6-(5-(Thiophen-2-yl)isoxazole-3-carboxamido)hexyl 5-((3aS,4S,6aR)-2-oxohexahydro-1H-thieno[3,4-d]imidazol-4-yl)pentanoate Purity: 98% by TLC nMR (Conforms) Store -20°C Ship Rt (1 per EA )

Manufacturer: Focus Biomolecules

SKU
10-5400-5mg-EA
Biotin-isoxazole, Precipitates RNA Binding Proteins, 5mg, CAS# 1377605-22-5 is available to buy in increments of 1

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Exposure of cell or tissue lysates to biotin-isoxazole precipitates hundreds of RNA-binding proteins with significant overlap to the constituents of RNA granules.1,2 In one study roughly 580 nuclear proteins were identified as being precipitated by B-Isox including TAF15, RNA polymerase II (largest subunit), numerous subunits of the mediator complex as well as a variety of enzymes involved in epigenetic modification of histones.3 SR domains were found to be the determinant that facilitates B-Isox precipitation.4 Also allows for the fractionation / isolation of SG-associated proteins and RNA precipitates.5

CAS Number: 1377605-22-5

Manufacturer Part Number/SKU: 10-5400-5mg-EA

Tags: Focus Biomolecules