BI_749327, Selective TRPC6 antagonist, 25mg, CAS# 2361241-23-6
$300.00
[4-(6-Aminopyridazin-3-yl)piperidin-1-yl]-[4-[4-(trifluoromethyl)phenoxy]phenyl]methanone Purity: 98% by HPLC NMR (Conforms) Store -20°C Ship RT (1 per EA )
Manufacturer: Focus Biomolecules
SKU
10-4318-25mg-EA
BI_749327, Selective TRPC6 antagonist, 25mg, CAS# 2361241-23-6 is available to buy in increments of 1
Product Details
Download Details and SpecificationsPotent (IC50 = 13 nM mouse TRPC6, 19 nM human TRPC6) and selective (85-fold over TRPC3, 42-fold over TRC7) orally available blocker of TRPC6.1 It suppressed interstitial fibrosis and associated molecular signaling in mouse heart and kidney disease models. BI 749327 reversed established pulmonary hypertension by 50% via regression of pulmonary remodeling in a mouse model.2
CAS Number: 2361241-23-6
Manufacturer Part Number/SKU: 10-4318-25mg-EA
Tags: Focus Biomolecules