BG45, HDAC3 selective inhibitor, 5mg, CAS# 926259-99-6
$60.00
N-(2-Aminophenyl)-2-pyrazinecarboxamide Purity: >98% by HPLC NMR (Conforms) Store -20°C Ship RT (1 per EA )
Manufacturer: Focus Biomolecules
SKU
10-5638-5mg-EA
BG45, HDAC3 selective inhibitor, 5mg, CAS# 926259-99-6 is available to buy in increments of 1
Product Details
Download Details and SpecificationsPotent and selective HDAC3 inhibitor (IC50 = 289 nM), IC50s for HDAC1, 2 and 6 = 2, 2.2 and >20 mM respectively.1 Inhibits tumor growth in a mouse xenograft model of human multiple myeloma.1 Downregulates expression of DNA methyltransferase 1.2 Increases expression of synaptic proteins in exogenous Aβ-treated cells and mice.3 Rescues synaptic damage and neuron loss in APP-transfected cells (15 mM) and APP/PS1 mice (30 mg/kg).4
CAS Number: 926259-99-6
Manufacturer Part Number/SKU: 10-5638-5mg-EA
Tags: Focus Biomolecules