BADGE, PPARγ antagonist, 10mg, CAS# 1675-54-3
$30.00
2,3-Bis[4-(2,3-epoxypropoxy)phenyl]propane Purity: 95% by HPLC NMR (Conforms) Store -20°C Ship RT (1 per EA )
Manufacturer: Focus Biomolecules
SKU
10-2618-10mg-EA
BADGE, PPARγ antagonist, 10mg, CAS# 1675-54-3 is available to buy in increments of 1
Product Details
Download Details and SpecificationsPPARγ antagonist with μM affinity in 3T3-L1 and 3T3-F442A preadipocyte cells. Selective over PPARδ and PPARα. Antagonizes the ability of rosiglitazone to stimulate transcriptional activity of PPARγ and abolishes its anti-inflammatory effects in a mouse model1. Induces apoptosis via PPARγ-independent mechanisms2. Induces adipogenesis in human and mouse mesenchymal stromal stem cells and in mouse 3T3-L1 preadipocytes at low nM concentrations via a PPARγ independent mechanism3. Increases osteoblastogenesis and bone mass in a mouse model4. Active in vivo.
CAS Number: 1675-54-3
Manufacturer Part Number/SKU: 10-2618-10mg-EA
Tags: Focus Biomolecules