AZD7648, DNA-PK inhibitor/CRISPR enhancer, 25mg, CAS# 2230820-11-6
$240.00
7-Methyl-2-[(7-methyl-[1,2,4]triazolo[1,5-a]pyridine-6-yl)amino]-9-(oxan-4-yl)purin-8-one Purity: >98% by HPLC NMR (Conforms) Store -20°C Ship RT (1 per EA )
Manufacturer: Focus Biomolecules
SKU
10-4108-25mg-EA
AZD7648, DNA-PK inhibitor/CRISPR enhancer, 25mg, CAS# 2230820-11-6 is available to buy in increments of 1
Product Details
Download Details and SpecificationsAZD7648 is a very potent and selective (against 397 kinases) DNA-PK inhibitor (pIC50 = 9.2; cellular pIC50 = 7.0).1 It is a sensitizer of radiation- and doxorubicin-induced DNA damage and sustained tumor regression in xenograft and patient-derived xenograft models.2 AZD7648 significantly enhances precise CRISPR/Cas9 gene editing alone3,4,5 or in combined treatment with a DNA polymerase theta inhibitor (2iHDR cocktail)5.
CAS Number: 2230820-11-6
Manufacturer Part Number/SKU: 10-4108-25mg-EA
Tags: Focus Biomolecules