Axitinib, VEGFR kinase inhibitor, 50mg, CAS# 319460-85-0
$110.00
N-Methyl-[[3-[(1E)-2-(2-pyridinyl)ethenyl]-1H-indazol-6-yl]thio]benzamide Purity: 99% by HPLC Purity: NMR (Conforms) Store -20°C Ship RT (1 per EA )
Manufacturer: Focus Biomolecules
SKU
10-2118-50mg-EA
Axitinib, VEGFR kinase inhibitor, 50mg, CAS# 319460-85-0 is available to buy in increments of 1
Product Details
Download Details and SpecificationsPotent inhibitor of VEGFR-2, -3, and -1, IC50 = 0.2, 0.1-0.3, and 1.2 nM respectively1 displaying minimal activity against a panel of ~100 protein kinases. Inhibits angiogenesis and vascular permeability.2 Also inhibits BCR-ABL1 (T315I) with high potency, Ki = 149 pM for autophosphorylated ABL1 (T315I).3 Inhibits proliferation of Ba/F3 cells expressing BCR-ABL1 (T315I). Clinically useful anticancer agent.4
CAS Number: 319460-85-0
Manufacturer Part Number/SKU: 10-2118-50mg-EA
Tags: Focus Biomolecules