AS-1949490, SHIP2 inhibitor, 25mg, CAS# 1203680-76-5
$248.00
3-[(4-Chlorophenyl)methoxy]-N-[(1S)-1-phenylethyl]- 2-thiophenecarboxamide Purity: 98% by TLC NMR (conforms) Store -20°C Ship RT (1 per EA )
Manufacturer: Focus Biomolecules
SKU
10-5103-25mg-EA
AS-1949490, SHIP2 inhibitor, 25mg, CAS# 1203680-76-5 is available to buy in increments of 1
Product Details
Download Details and SpecificationsA potent and selective inhibitor of the intracellular phosphatase SHIP2 (SH2 domain-containing inositol 5'-phosphatase 2), IC50 = 0.62 mM.1 Displays ca. 30-fold selectivity for SHIP2 over SHIP1. Activates insulin signaling via the Akt pathway in liver and lowers glucose levels in diabetic mice.1,2 Enhances BDNF expression in cultured cortical neurons.3 Ameliorates ROS generation but aggravates apoptosis in CD2AP-deficient mouse podocytes.4
CAS Number: 1203680-76-5
Manufacturer Part Number/SKU: 10-5103-25mg-EA
Tags: Focus Biomolecules