Manufacturer: Focus Biomolecules
Activator of antioxidant response element (ARE) which induces cytoprotective genes in human cells. It alkylates Keap1 at Cys151 and is reactive toward additional cysteines at higher concentrations. Disrupts Nrf2/Keap1 and Keap1/Cul3 interactions and stabilizes Nrf2. Activates ARE in an Nrf2 and PI 3-kinase dependent manner. Cell permeable and active in vivo.
CAS Number: 882288-28-0
Manufacturer Part Number/SKU: 10-1497-25mg-EA
Tags: Focus Biomolecules