ABT-869, Dual VEGFR and PDGFR kinase inhibitor, 25mg, CAS# 796967-16-3
$175.00
1-(4-(3-Amino-1H-indazol-4-yl)phenyl)-3-(2-fluoro-5-methylphenyl)urea Purity: >98% by HPLC NMR (Conforms) Store -20°C Ship RT (1 per EA )
Manufacturer: Focus Biomolecules
SKU
10-5268-25mg-EA
ABT-869, Dual VEGFR and PDGFR kinase inhibitor, 25mg, CAS# 796967-16-3 is available to buy in increments of 1
Product Details
Download Details and SpecificationsABT-869 (796967-16-3) ia a structurally novel, potent inhibitor of receptor tyrosine kinases inhibiting VEGFR and PDGFR and related kinases with IC50s= 3, 4, 4, 66, 3 and 14 nM for VEGFR1, VEGFR2, FLT3, PDGFRβ, CSF-1R and KIT respectively.1,2 Protects cells from necroptosis and rescues SIRS mice from TNF-α-induced shock and death.3 Exerts anti-obesity effects by promoting adipocyte browning.4 Inhibits angiogenesis.5
CAS Number: 796967-16-3
Manufacturer Part Number/SKU: 10-5268-25mg-EA
Tags: Focus Biomolecules