ABT-263, Bcl-2 family inhibitor, Senolytic agent, 25mg, CAS# 923564-51-6

ABT-263, Bcl-2 family inhibitor, Senolytic agent, 25mg, CAS# 923564-51-6

NSC59984, p53 activator, 25mg, CAS# 803647-40-7

NSC59984, p53 activator, 25mg, CAS# 803647-40-7

ABT-263, Bcl-2 family inhibitor, Senolytic agent, 5mg, CAS# 923564-51-6

$60.00
4-[4-[[2-(4-chlorophenyl)-5,5-dimethyl-1-cyclohexen-1-yl]methyl]-1-piperazinyl]-N-[[4-[[(1R)- 3-(4-morpholinyl)-1-[(phenylthio)methyl]propyl]amino]-3-[(trifluoromethyl)sulfonyl]-phenyl]sulfonyl]-benzamide Purity: 98% by HPLC Store -20°C Ship RT (1 per EA )

Manufacturer: Focus Biomolecules

SKU
10-3141-5mg-EA
ABT-263, Bcl-2 family inhibitor, Senolytic agent, 5mg, CAS# 923564-51-6 is available to buy in increments of 1

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Potent and selective Bcl-2 family inhibitor / BH3 domain mimetic which binds to Bcl-2, Bcl-xL and Bcl-w (Ki<1 nM). A useful tool compound which has shown interesting results in various cancer clinical trials2. Synergizes with deoxyglucose and other agents, inducing apoptosis in cancer cells in a xenograft mouse model3. A novel senolytic agent, inducing apoptosis preferentially in senescent cells in a cell type-restricted manner4.

CAS Number: 923564-51-6

Manufacturer Part Number/SKU: 10-3141-5mg-EA

Tags: Focus Biomolecules