AA43279, Nav 1.1 activator, 25mg, CAS# 354812-16-1
$200.00
3-Amino-5-(4-methoxyphenyl)thiophene-2-carboxamide Purity: 97% by TLC NMr (Conforms) Store -20°C Ship RT (1 per EA )
Manufacturer: Focus Biomolecules
SKU
10-3503-25mg-EA
AA43279, Nav 1.1 activator, 25mg, CAS# 354812-16-1 is available to buy in increments of 1
Product Details
Download Details and SpecificationsSelective Nav1.1activator. In HEK-293 cells expressing human Nav1.1 channels AA43279 increased the Nav1.1-mediated current in a concentration dependent manner (EC50=9.5 µM). In rat hippocampal brain slices it increased the firing activity parvalbumin-expressing, fast-spiking GABAergic interneurons and increased the spontaneous inhibitory post-synaptic currents recorded from pyramidal neurons. It displayed anticonvulsant activity in vivo. Important tool compound for exploring the physiology of Nav1.1 channels.1
CAS Number: 354812-16-1
Manufacturer Part Number/SKU: 10-3503-25mg-EA
Tags: Focus Biomolecules