A-438079 HCl, P2X7 antagonist, 5mg, CAS# 899431-18-6
$60.00
3-[5-(2,3-Dichlorophenyl)tetrazol-1-ylmethyl]pyridine hydrochloride Purity: 98% by HPLC NMR (Conforms) Store -20°C Ship RT (1 per EA )
Manufacturer: Focus Biomolecules
SKU
10-4063-5mg-EA
A-438079 HCl, P2X7 antagonist, 5mg, CAS# 899431-18-6 is available to buy in increments of 1
Product Details
Download Details and SpecificationsA-438079 (899431-18-6) is a competitive P2X7 receptor antagonist (pIC50 = 6.9).1 Displayed antinociceptive effects in a rat model of neuropathic pain.2 A-438079 prevented the LPS-induced release of IL-1ß and attenuated LPS-induced (via intrathecal lumbar injection) mechanical hyperalgesia in rat hindpaws.3 It prevented mechanical hyperalgesia following peripheral nerve injury.4 A-438079 protected against cerebral ischemia/reperfusion injury in a rat model via reduction of the neuroinflammatory response.5
CAS Number: 899431-18-6
Manufacturer Part Number/SKU: 10-4063-5mg-EA
Tags: Focus Biomolecules