680C91, Tryptophan 2,3-dioxygenase inhibitor, 5mg, CAS# 163239-22-3
$68.00
6-Fluoro-3-[(1E)-2-(3-pyridinyl)ethenyl]-1H-indole Purity: 98% by TLC Purity: NMR (Conforms) Store -20°C Ship RT (1 per EA )
Manufacturer: Focus Biomolecules
SKU
10-1443-5mg-EA
680C91, Tryptophan 2,3-dioxygenase inhibitor, 5mg, CAS# 163239-22-3 is available to buy in increments of 1
Product Details
Download Details and SpecificationsA potent and selective inhibitor of tryptophan 2,3-dioxygenase (TDO) Ki=42 nM)1,2. Displays no activity against indoleamine 2,3-dioxygenase, MAO-A and B and does not effect serotonin uptake. Elevates CSF tryptophan by up to 260% and CSF serotonin by 170% of basal2. TDO inhibition by 680C91 in glioma cells blocked the release of kynurenine, an endogenous tumor promoting AHR ligand4.
CAS Number: 163239-22-3
Manufacturer Part Number/SKU: 10-1443-5mg-EA
Tags: Focus Biomolecules