5-Fluorouracil, Thymidylate synthase inhibitor, 1g, CAS# 51-21-8
$30.00
5-Fluoro-1H,3H-pyrimidine-2,4-dione Purity: 0.98 Store -20°C Ship RT (1 per EA )
Manufacturer: Focus Biomolecules
SKU
10-1276-1g-EA
5-Fluorouracil, Thymidylate synthase inhibitor, 1g, CAS# 51-21-8 is available to buy in increments of 1
Product Details
Download Details and Specifications5-Fluorouracil (5-FU) is a clinically useful anticancer agent that acts via irreversible inhibition of thymidylate synthase. The active metabolites of 5-FU are 5-Fluorodeoxyuridylate (5-FdUMP), 5-Fluorodeoxyuridine triphosphate (5-FdUTP) and 5-Fluorouridine triphosphate (5-FUTP). The primary cytotoxic effect of 5-FU is believed to be inhibition of thymidylate synthase by 5-FdUMP. Secondary effects include incorporation of 5-FdUTP into DNA resulting in DNA strand breaks and incorporation of 5-FUTP into RNA causing abnormal RNA processing.1
CAS Number: 51-21-8
Manufacturer Part Number/SKU: 10-1276-1g-EA
Tags: Focus Biomolecules