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4-Octyl itaconate, Nrf2 activator, 20mg, CAS# 3133-16-2

$50.00
4-Octyl methylenesuccinate; n-Octyl 3-carboxy-3-butenoate Purity: >98% by TLC NMR (Conforms) Store -20°C Ship RT (1 per EA )

Manufacturer: Focus Biomolecules

SKU
10-3573-20mg-EA
4-Octyl itaconate, Nrf2 activator, 20mg, CAS# 3133-16-2 is available to buy in increments of 1

Product Details

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4-Octyl itaconate is a cell-permeable analog of itaconic acid which activates the anti-inflammatory transcription factor Nrf2 via alkylation of KEAP1.1 It inhibits various forms of cell death including ferroptosis2 and gasdermin B-mediated pyroptosis3 while inducing secretion of anti-inflammatory proteins4 and promoting a wound-resolving phenotype in pro-inflammatory macrophages5.

CAS Number: 3133-16-2

Manufacturer Part Number/SKU: 10-3573-20mg-EA

Tags: Focus Biomolecules