2-AAPA, Glutathione and thioredoxin reductase inhibitor, 5mg, CAS# 1133387-90-2
$60.00
R,R'-2-Acetylamino-3-[4-(2-acetylamino-2-carboxyethylsulfanylthiocarbonylamino)-phenylthiocarbamoylsulfanyl]propionic acid Purity: hydrate Purity: 98% by HPLC Store -20°C Ship RT (1 per EA )
Manufacturer: Focus Biomolecules
SKU
10-3238-5mg-EA
2-AAPA, Glutathione and thioredoxin reductase inhibitor, 5mg, CAS# 1133387-90-2 is available to buy in increments of 1
Product Details
Download Details and SpecificationsInhibits glutathione reductase and thioredoxin reductase,IC50s=6.7 and 8.7 µM respectively, and impairs mitochondrial function.1 May be used to induce a cellular model of thiol oxidative stress.2 Enhances sensitivity of cancer cell lines to X-ray irradiation.3 Induces G2/M cell cycle arrest by inducing thiol oxidative stress resulting in α-tubulin S-glutathionylation-mediated microtubule depolymerization.4 Improves limb revascularization by glutathionylation and subsequent stabilization of HIF-1α.5
CAS Number: 1133387-90-2
Manufacturer Part Number/SKU: 10-3238-5mg-EA
Tags: Focus Biomolecules